Rodent Glucose Clamp

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Mouse insulin and glucose studies can be conducted safely and efficiently with the right high-quality supplies from SAI.

Insulin sensitivity studies can become complex and challenging, but we are here to provide the support and resources you need for success. Whether your research involves Glucose Tolerance Tests (GTT), Hyperglycemic Clamp techniques, or Hyperinsulinemic-Euglycemic Clamp protocols, we offer expert guidance and tailored recommendations to streamline your process. Explore our curated selection of supplies and solutions below to ensure your studies are conducted with precision, reliability, and ease.

Supplies for ITT and GTT Studies

In this study design, a loading dose of glucose (gtt) or insulin (itt) is followed by intermittent blood sampling. The dose is typically administered orally, and since multiple blood samples are needed, an access port is the best tool to make catheter access quick and easy.

  • Silicone Mouse Jugular Catheter Beads at 11 and 29mm

    Our biocompatible polyurethane and silicone catheters are designed to enhance patency and minimize vessel trauma during implantation. All these catheters have beads accurately positioned from the catheter tip for optimal implantation position within the vessel. Beads are also positioned to provide a secure tension loop to maximize continued patency during[...]

    Select options This product has multiple variants. The options may be chosen on the product page
  • Disposable Feeding Needle, Rat, Sterile, 100mm, Grey with Bite Guard

    These PTFE feeding needles are designed to reduce the risk of trauma and bite-through, providing a safe, low cost, disposable, solution for oral gavage. SAI's affordable feeding tubes boast distinct features, including a soft silicone tip, a smooth plastic PTFE shaft and an optional, bite-resistant, stainless steel bite-guard for maximum[...]

    Select options This product has multiple variants. The options may be chosen on the product page
  • CannuLock™ Ports, 25G Red, 10 sterile pouches of 2 each, 20 ports total

    SAI's Catheter Access Ports™ offer all new CannuLock™ technology, providing a remarkably secure connection between your catheter and the port. The carefully designed barbed connector locks with the catheter to eliminate the risk of slipping or disconnecting. CannuLock™ technology is also available in our Catheter Access Button™. Smooth barb safely "locks"[...]

    Select options This product has multiple variants. The options may be chosen on the product page

Supplies for Hyperglycemic Clamp Studies

In this study design, glucose is infused intravenously with adjustments to reach a steady state. From there, intermittent blood samples are collected and analyzed to establish glucose levels. Since the mouse must be tethered, and low-stress, the CannuLock™ Catheter Access Button™ is an ideal tool.

  • Silicone Mouse Jugular Catheter Beads at 11 and 29mm

    Our biocompatible polyurethane and silicone catheters are designed to enhance patency and minimize vessel trauma during implantation. All these catheters have beads accurately positioned from the catheter tip for optimal implantation position within the vessel. Beads are also positioned to provide a secure tension loop to maximize continued patency during[...]

    Select options This product has multiple variants. The options may be chosen on the product page
  • Mouse Arterial Catheters without Stylet

    Our biocompatible catheters for the carotid artery of the mouse are designed for accurate placement to maximize patency. They are sized to fit into small mouse vessels, with suture beads located for optimal positioning. These catheters may be used for blood pressure measurement or infusion. A complete list of our mouse[...]

    Select options This product has multiple variants. The options may be chosen on the product page
  • Bile collection 25G swivel to tube extension lines 3/pk

    This extension line is a perfect fit for our CannuLock™ Bile Collection System. The polyurethane tubing is press fit to the 25G dual pin swivel and runs from the top of the swivel down to your collection vial. 3/pk, ETO sterilized Fits 25G Swivel Connection 33″ length, or request the[...]

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  • CannuLock™ Ports, 25G Red, 10 sterile pouches of 2 each, 20 ports total

    SAI's Catheter Access Ports™ offer all new CannuLock™ technology, providing a remarkably secure connection between your catheter and the port. The carefully designed barbed connector locks with the catheter to eliminate the risk of slipping or disconnecting. CannuLock™ technology is also available in our Catheter Access Button™. Smooth barb safely "locks"[...]

    Select options This product has multiple variants. The options may be chosen on the product page
  • 12” Tether, Dual Channel CABM, 25G P1 and P2

    SAI's Mouse Catheter Access Buttons™ offer all new CannuLock™ technology, providing a remarkably secure connection for one or two catheters. Our single and dual channel tethers make connections even easier with a quick magnetic connection and smart alignment features. Mouse Catheter Access Button™ Tethers Open spring design relieves weight bearing and reduces torque on mice. 12"[...]

    Select options This product has multiple variants. The options may be chosen on the product page
  • Dual Channel CannuLock™ Catheter Access Button™ for Mouse, 25G

    Safe and secure Mouse Catheter Access Buttons™ feature CannuLock™ technology, providing a remarkably secure connection for one or two catheters. The smooth barbed connector locks with the catheter to eliminate the risk of slipping or disconnecting. An optional Stabilizing Tool and Protective Cap make it easier than ever to protect your mice[...]

    Select options This product has multiple variants. The options may be chosen on the product page

Supplies for Hyperinsulinemic-Euglycemic Clamp Studies

This protocol relies on intravenous (IV) infusion of insulin to set a baseline, as well as variable rate infusion of glucose (into the same IV line). It’s also common to incorporate an additional channel to dose an experimental compound. Intermittent blood sampling for glucose levels will determine the impact of the drug administration on the mouse.

  • Silicone Mouse Jugular Catheter Beads at 11 and 29mm

    Our biocompatible polyurethane and silicone catheters are designed to enhance patency and minimize vessel trauma during implantation. All these catheters have beads accurately positioned from the catheter tip for optimal implantation position within the vessel. Beads are also positioned to provide a secure tension loop to maximize continued patency during[...]

    Select options This product has multiple variants. The options may be chosen on the product page
  • Mouse Arterial Catheters without Stylet

    Our biocompatible catheters for the carotid artery of the mouse are designed for accurate placement to maximize patency. They are sized to fit into small mouse vessels, with suture beads located for optimal positioning. These catheters may be used for blood pressure measurement or infusion. A complete list of our mouse[...]

    Select options This product has multiple variants. The options may be chosen on the product page
  • Bile collection 25G swivel to tube extension lines 3/pk

    This extension line is a perfect fit for our CannuLock™ Bile Collection System. The polyurethane tubing is press fit to the 25G dual pin swivel and runs from the top of the swivel down to your collection vial. 3/pk, ETO sterilized Fits 25G Swivel Connection 33″ length, or request the[...]

    Add to cart
  • CannuLock™ Ports, 25G Red, 10 sterile pouches of 2 each, 20 ports total

    SAI's Catheter Access Ports™ offer all new CannuLock™ technology, providing a remarkably secure connection between your catheter and the port. The carefully designed barbed connector locks with the catheter to eliminate the risk of slipping or disconnecting. CannuLock™ technology is also available in our Catheter Access Button™. Smooth barb safely "locks"[...]

    Select options This product has multiple variants. The options may be chosen on the product page
  • 12” Tether, Dual Channel CABM, 25G P1 and P2

    SAI's Mouse Catheter Access Buttons™ offer all new CannuLock™ technology, providing a remarkably secure connection for one or two catheters. Our single and dual channel tethers make connections even easier with a quick magnetic connection and smart alignment features. Mouse Catheter Access Button™ Tethers Open spring design relieves weight bearing and reduces torque on mice. 12"[...]

    Select options This product has multiple variants. The options may be chosen on the product page
  • Dual Channel CannuLock™ Catheter Access Button™ for Mouse, 25G

    Safe and secure Mouse Catheter Access Buttons™ feature CannuLock™ technology, providing a remarkably secure connection for one or two catheters. The smooth barbed connector locks with the catheter to eliminate the risk of slipping or disconnecting. An optional Stabilizing Tool and Protective Cap make it easier than ever to protect your mice[...]

    Select options This product has multiple variants. The options may be chosen on the product page